ImmunoComb® Bovine Nespora is a user-friendly assay based on the dot-ELISA principle for determining antibody levels to N. caninum in bovine serum or whole blood. Neospora caninum is a newly recognized protozoan parasite that has been reported in various species of livestock. Recently, neosporosis has been identified as an important cause of abortion in bovine. Neospora related abortions occur in both dairy and beef cattle; the most severe problems have been noted in dairy operations. Two patterns of abortion, endemic and epidemic, are associated with neospora infection. In herds with endemic abortion, neospora seropositive cows are 2-3 times more likely to abort than their seronegative herdmates. The risk of abortion in an epidemic ‘storm’ can be 20-50 fold for neospora seropositive cows. Abortions typically occur in mid to late gestation (4 – 8 months).